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	Comments on: How clinical judgement can strengthen evidence-based medicine	</title>
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		By: Clinical evidence development: rare disease market access in Europe		</title>
		<link>https://mtechaccess.co.uk/clinical-judgement-evidence-based-medicine/#comment-74</link>

		<dc:creator><![CDATA[Clinical evidence development: rare disease market access in Europe]]></dc:creator>
		<pubDate>Thu, 04 Feb 2021 11:45:30 +0000</pubDate>
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					<description><![CDATA[[&#8230;] Due to the small target population and the severity of most rare diseases, trial design and enrolment is challenging and far from the ideal double-blinded, comparative, parallel design of gold-standard randomised clinical trials. My colleague, Shona Lang, recently explored this and other related challenges in her article ‘How clinical judgement can strengthen evidence-based medicine’. [&#8230;]]]></description>
			<content:encoded><![CDATA[<p>[&#8230;] Due to the small target population and the severity of most rare diseases, trial design and enrolment is challenging and far from the ideal double-blinded, comparative, parallel design of gold-standard randomised clinical trials. My colleague, Shona Lang, recently explored this and other related challenges in her article ‘How clinical judgement can strengthen evidence-based medicine’. [&#8230;]</p>
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